Take the next step with MyRisk

Get started by downloading the provider guide or explore ordering options to bring MyRisk to your practice.

Download provider overview

Take the next step with MyRisk

Whether you’ve heard about genetic testing before or want to learn more, we can help provide in-depth information on MyRisk and your testing options.

Download patient guide

Meet Fiona, a Myriad Oncology patient, who has taken a MyRisk® Hereditary Cancer test

MyRisk® Hereditary Cancer Test

Impact medical management decisions throughout the cancer care journey

MyRisk evaluates 48 clinically actionable genes to provide a comprehensive, guideline-driven assessment across 11 common cancer sites, empowering healthcare providers to personalize care plans.

Enhanced insights no matter where your patients are in their treatment journey

Guide treatment decisions right from diagnosis

MyRisk provides you with more critical answers for more patients by definitively classifying up to 63% of variants that other labs could not.1

Unlock targeted therapy opportunities

Did you know that up to 10% of germline variants are missed by tumor testing alone?2 MyRisk identifies germline BRCA1/2 variants that may impact use of targeted therapies such as PARP inhibitors.3,4

Identify risk of secondary cancer and personalize management

MyRisk identifies hereditary cancer syndromes associated with a risk for secondary cancers, directly impacting treatment decisions to reduce the occurrence of subsequent cancer.

Get results within 14 days, and as fast as 7 days with MyRisk STAT priority ordering option

Graphic showing the how MyRisk® Germline test can guide treatment decisions, including targeted therapy options and identify the risk for secondary cancer

Germline testing info graphic

Meet germline testing guidelines confidently with MyRisk

National Guidelines recommend germline testing as part of the workup for patients diagnosed with ovarian, breast, pancreatic, prostate, and colon cancer.6 Additionally, while genomic testing has long been recommended for all patients diagnosed with metastatic or advanced cancers, the American Society of Clinical Oncology (ASCO) now advises multigene germline testing for patients who meet criteria regardless of their tumor results.2

Who is MyRisk for?

Image showing the Myriad Oncology MyRisk test kit

MyRisk germline testing is appropriate for patients diagnosed with:

  • Breast cancer*
  • Ovarian cancer
  • Prostate cancer
  • Pancreatic cancer*
  • Uterine cancer
  • Colorectal cancer
  • Skin cancer
  • Gastric cancer
  • Renal cancer
  • Lung cancer
  • Endocrine cancer
  • Other

*eligible for MyRisk STAT

MyRisk provides you with clear, actionable results

MyRisk germline testing assesses 48 genes linked to one or more of 11 cancer sites.

Every MyRisk test report includes:

  • Germline results with clinically significant mutations found, including variants of uncertain significance (VUS)
  • Summary of clinical, personal, and family cancer history
  • The Myriad Management Tool, providing risk estimates, critical information for treatment decisions based on test results, as well as personalized medical management recommendations in line with current guidelines
  • Information to help family members understand their potential genetic risk
Image of sample positive, elevated, and negative MyRisk® Hereditary Cancer Test results
Positive result icon

Positive Result

A mutation has been identified.

Elevated result icon

Elevated Result

An elevated risk has been identified.

Negative result icon

Negative Result

No clinically significant mutation.

Variant of uncertain significance result icon

Variant of Uncertain Significance

Mutation of uncertain risk has been identified.

Accurate testing that goes beyond patients’ initial test results

Myriad is the industry leader in variant classification and reclassification. We use proprietary variant classification tools, including RNA testing and other cutting-edge technology, to provide comprehensive, clinically actionable and iaccurate results.

MyRisk offers the industry’s lowest reported rates of BRCA1/2 VUS of <1.0%1,3

Our Lifetime Classification Commitment sends amended reports whenever a patient’s MyRisk VUS result is reclassified as clinically significant

MyRisk definitively classifies
up to 63%
of variants other labs could not5

RNA analysis delivers cutting-edge innovation

Myriad pioneered the use of RNA analysis in 2015 and offers RNA analysis to all patients
with an eligible VUS, giving providers and patients access to this valuable tool at no additional cost.

MyRisk STAT:

Right surgery. Right answer. Right now.

There should not be a trade-off between turnaround time and receiving an accurate, comprehensive risk assessment when determining surgical treatment for patients. MyRisk STAT was developed for trusted results without the wait.

7 days

MyRisk STAT test results for Breast and Pancreatic cancer patients

<14 days

Results delivered for all other patients

How to test with MyRisk

Provider completes the test request form (in the portal or via paper TRF)

Provider completes the test request form (in the portal or via paper TRF)

Patient blood or saliva sample is collected and submitted to Myriad Genetics with the test kit

Patient blood or saliva sample is collected and submitted to Myriad Genetics with the test kit

Results are sent to the ordering provider (in the portal or via mail)

Results are sent to the ordering provider (in the portal or via mail)

Image showing Myriad Oncology’s portfolio of germline and tumor genomic test kits

One simple order. Comprehensive results.

With Myriad Oncology, you can receive comprehensive results for germline and tumor genomic testing in one single ordering experience, getting clear, fast answers for your patients.

Myriad Oncology empowers you to transform patient care

For a complete approach to cancer risk management and treatment planning, MyRisk germline should be combined with tumor genomic testing to deliver powerful results informing patient care across the entire journey-from assessing hereditary cancer syndromes to guiding treatment decisions.

Precise Tumor® Molecular Profile Test

For your patients with advanced cancer, combine germline and tumor genomic insights to identify hereditary cancer risks and actionable mutations, enabling personalized treatment plans and targeted therapies. MyRisk and Precise Tumor focus on clinically relevant variations in the genome, where each test couples RNA analysis with DNA sequencing to provide more refined interpretation of results.

Endopredict Breast Cancer prognostic Test Precise Tumor® Molecular Profile Test

For your patients with early-stage breast cancer, pair germline testing with tumor genomic insights and breast cancer recurrence assessment to guide personalized decisions on risk-reducing surgeries and adjuvant therapy strategies.

MyChoice companion diagnostic Precise Tumor® Molecular Profile Test

For your patients with ovarian cancer at any stage, integrate germline and tumor genomic insights with tumor homologous recombination deficiency (HRD) testing to inform comprehensive treatment options with PARP inhibitors.

Myriad Oncology’s portfolio of products delivers:

  • Integrated genetic and tumor genomic insights to personalize care for each cancer patient
  • Confident risk and recurrence assessments to inform both preventive and therapeutic decisions
  • Streamlined reporting to prioritize actionable insights at every step of the cancer journey

What to expect with every MyRisk test

Actionable

Every MyRisk test delivers treatment-focused reporting with actionable summaries, providing clear guidance for surgical and treatment decisions to support more confident patient care.

Accurate

MyRisk delivers unmatched accuracy, with variant classification techniques independently verified and clinically validated at >99.9% accuracy.3

Affordable

Transparent pricing with personalized cost estimates, financial assistance, and other affordability options including direct pay.

MyRisk resources

NCCN = National Comprehensive Cancer Network® (NCCN®)

Patients with government payers (Medicare, Medicare Advantage, TriCare) are not eligible for MyRisk STAT.

References:
  1. Gradishar W, Iqbal N, Parker J, et al. Clinical variant classification: a comparison of public databases and a commercial testing laboratory. Oncologist. 2017;22(7):797-803.
  2. Tung N, Ricker C, Messersmith H, et al. Selection of Germline Genetic Testing Panels in Patients With Cancer: ASCO Guideline. J Clin Oncol. 2024;42(21):2599-2615.
  3. Judkins T, et al. Development and analytical validation of a 25-gene next-generation sequencing panel that includes BRCA1 and BRCA2 genes to assess hereditary cancer risk. BMC Cancer. 2015;15:215.
  4. Mundt E, Iorg G. Driving Down the Rate of Variants of Uncertain Significance as the Myriad MyRisk® Multigene Panel Grows [White paper]. Myriad Genetics. 2020
  5. Internal data on file at Myriad Genetics, Inc.
  6. National Comprehensive Cancer Network (NCCN). NCCN Clinical Practice Guidelines in Oncology: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2024. Plymouth Meeting, PA: National Comprehensive Cancer Network; 2023. Available at: https://www.nccn.org/guidelines/category_1. Accessed October 21, 2024.

Myriad Genetics, MyRisk, Precise Tumor, MyChoice, Prolaris, BRACAnalysis CDx, RiskScore, and their respective logos, are registered trademarks of Myriad Genetics, Inc. and its subsidiaries in the United States and other jurisdictions. EndoPredict and the EndoPredict logo are either trademarks or registered trademarks of Eurobio Scientific.